Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 12/20 | 0.59 |
| ▸ | PDE5A | O76074 | 2/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947698 | 0.83 | PDE5A (0.60) | PDE4BPDE5ANR3C1 | |
| SCHEMBL4348757 | 0.82 | PDE4B (0.85) | PDE4BPDE5ANR3C1 | |
| SCHEMBL7961851 | 0.81 | PDE4B (0.57) | PDE4BPDE5ANR3C1 | |
| SCHEMBL7947992 | 0.81 | PDE4B (0.57) | PDE4BPDE5ANR3C1 | |
| SCHEMBL7947996 | 0.81 | PDE4B (0.57) | PDE4BPDE5ANR3C1 | |
| SCHEMBL7947714 | 0.80 | PDE5A (0.58) | PDE4BPDE5ANR3C1PGR | |
| SCHEMBL7955223 | 0.79 | PDE5A (0.61) | PDE4BPDE5ANR3C1PGR | |
| SCHEMBL4339585 | 0.77 | PDE4B (0.72) | PDE4BPDE5ANR3C1 | |
| SCHEMBL4335267 | 0.77 | PDE4B (0.71) | PDE4BPDE5ANR3C1 | |
| SCHEMBL7947832 | 0.76 | PDE5A (0.60) | PDE4BPDE5ANR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |