Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955223 | 0.82 | PDE5A (0.61) | PDE5ANR3C1PDE4BPGR | |
| SCHEMBL7947992 | 0.81 | PDE4B (0.57) | PDE5ANR3C1PDE4B | |
| SCHEMBL7961851 | 0.81 | PDE4B (0.57) | PDE5ANR3C1PDE4B | |
| SCHEMBL7947996 | 0.81 | PDE4B (0.57) | PDE5ANR3C1PDE4B | |
| SCHEMBL7947692 | 0.80 | PDE4B (0.59) | PDE5ANR3C1PDE4BPGR | |
| SCHEMBL7955535 | 0.80 | PDE5A (0.72) | PDE5ANR3C1PDE4BPGR | |
| SCHEMBL7947832 | 0.80 | PDE5A (0.60) | PDE5ANR3C1PDE4BPGR | |
| SCHEMBL4338651 | 0.80 | NR3C1 (0.82) | PDE5ANR3C1PDE4BPGR | |
| SCHEMBL4339585 | 0.79 | PDE4B (0.72) | PDE5ANR3C1PDE4B | |
| SCHEMBL4335267 | 0.78 | PDE4B (0.71) | PDE5ANR3C1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |