Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.44 |
| ▸ | RXRA | P19793 | 7/20 | 0.44 |
| ▸ | RXRB | P28702 | 6/20 | 0.44 |
| ▸ | RARB | P10826 | 9/20 | 0.43 |
| ▸ | RARG | P13631 | 9/20 | 0.43 |
| ▸ | RARA | P10276 | 8/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929446 | 0.88 | RXRA (0.55) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL7949488 | 0.84 | RXRA (0.43) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL7947687 | 0.82 | CYP3A4 (0.42) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL7949336 | 0.76 | RXRA (0.69) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL7923000 | 0.73 | RXRA (0.49) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL2788640 | 0.72 | CYP3A4 (0.70) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL7923059 | 0.72 | RXRA (0.55) | CYP26A1RXRARXRBRARBRARG | |
| SCHEMBL20398885 | 0.72 | CYP3A4 (0.57) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL9120878 | 0.72 | CYP3A4 (0.57) | CYP3A4CYP26A1RXRARXRBRARB | |
| SCHEMBL17049073 | 0.72 | CYP3A4 (0.54) | CYP3A4CYP26A1RXRARXRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |