Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.55 |
| ▸ | RXRB | P28702 | 9/20 | 0.55 |
| ▸ | RARB | P10826 | 12/20 | 0.51 |
| ▸ | RARG | P13631 | 12/20 | 0.51 |
| ▸ | RARA | P10276 | 11/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.51 |
| ▸ | RXRG | P48443 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947694 | 0.88 | CYP3A4 (0.47) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7949336 | 0.86 | RXRA (0.69) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7923059 | 0.83 | RXRA (0.55) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7923000 | 0.81 | RXRA (0.49) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7932924 | 0.75 | RARA (0.55) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7947687 | 0.73 | CYP3A4 (0.42) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7931988 | 0.73 | RXRA (0.40) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7929418 | 0.73 | RARB (0.50) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7949488 | 0.72 | RXRA (0.43) | RXRARXRBRARBRARGRARA | |
| SCHEMBL7931172 | 0.72 | RXRA (0.70) | RXRARXRBRARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | claimed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | claimed |
| EP-0879223-B1 | AROMATIC POLYCYCLIC RETINOID-TYPE DERIVATIVES, METHOD FOR PREPARING SAME, AND USE THEREOF FOR MAKING PHARMACEUTICAL AND COSMETIC COMPOSITIONS | CT EUROP DE BIOPROSPECTIVE CEB (FR) | 2001-11-07 | — | — | EP | disclosed |
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |