Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | RARG | P13631 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 4/20 | 0.41 |
| ▸ | RXRB | P28702 | 9/20 | 0.41 |
| ▸ | RXRG | P48443 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923059 | 0.89 | RXRA (0.55) | RXRARARBRARGRARARXRB | |
| SCHEMBL7947694 | 0.84 | CYP3A4 (0.47) | RXRACYP3A4RARBRARGRARA | |
| SCHEMBL7941372 | 0.80 | RXRA (0.43) | RXRACYP3A4RARBRARGRARA | |
| SCHEMBL7931172 | 0.74 | RXRA (0.70) | RXRARARBRARGRARARXRB | |
| SCHEMBL14785605 | 0.73 | RARB (0.56) | RXRACYP3A4RARBRARGRARA | |
| SCHEMBL6905878 | 0.73 | RXRA (0.77) | RXRACYP3A4RARBRARGRARA | |
| SCHEMBL6902498 | 0.73 | RXRA (0.60) | RXRACYP3A4RARBRARGRARA | |
| SCHEMBL17049057 | 0.73 | CYP3A4 (0.47) | RXRACYP3A4RARBRARGRARA | |
| SCHEMBL727058 | 0.73 | RXRA (0.68) | RXRARARBRARGRARARXRB | |
| SCHEMBL7929446 | 0.72 | RXRA (0.55) | RXRACYP3A4RARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265423-B1 | SKIN DISORDERS; ANTICANCER AGENTS | CENTRE EUROPEEN DE BIOPROSPECTIVE-CEB (FR) | 2001-07-24 | — | — | US | disclosed |