SCHEMBL7947818

SCHEMBL7947818

C[C@@H](C=O)NC(=O)[C@@H](N)CCC(N)=O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 9/20 0.61
DPP9 Q86TI2 9/20 0.61
DPP4 P27487 6/20 0.61
BLM P54132 2/20 0.46
ALOX15 P16050 1/20 0.46
PMP22 Q01453 1/20 0.46
KMT2A Q03164 1/20 0.46
SLC15A1 P46059 1/20 0.38
DPP7 Q9UHL4 8/20 0.35
PAX8 Q06710 1/20 0.34
BMP1 P13497 1/20 0.31
CTSD P07339 1/20 0.31
BACE1 P56817 1/20 0.31
LMNA P02545 1/20 0.31
NOD1 Q9Y239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7947817 1.00 DPP8 (0.61) DPP8DPP9DPP4BLMALOX15
SCHEMBL7762244 0.82 DPP8 (0.69) DPP8DPP9DPP4BLMALOX15
SCHEMBL10940865 0.82 DPP8 (0.69) DPP8DPP9DPP4BLMALOX15
SCHEMBL17347919 0.81 DPP4 (0.55) DPP8DPP9DPP4BLMALOX15
SCHEMBL5579743 0.79 DPP4 (0.39) DPP8DPP9DPP4BLMALOX15
SCHEMBL30799779 0.79 DPP8 (0.65) DPP8DPP9DPP4BLMALOX15
SCHEMBL8560140 0.78 PAX8 (0.45) DPP8DPP9DPP4SLC15A1DPP7
SCHEMBL10067240 0.78 DPP9 (0.44) DPP8DPP9DPP4SLC15A1DPP7
SCHEMBL2739683 0.78 DPP9 (0.44) DPP8DPP9DPP4SLC15A1DPP7
SCHEMBL2739682 0.78 DPP9 (0.44) DPP8DPP9DPP4SLC15A1DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001054729-A1 TREATMENT OF NEUROPSYCHIATRIC DISEASE WITH PROTEASE AND NEURAMINIDASE INHIBITORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ASREPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2001-08-02 WO disclosed