Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | CPA2 | P48052 | 1/20 | 0.33 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764311 | 0.80 | SIRT5 (0.51) | DPP4DPP8DPP9BMP1TASP1 | |
| SCHEMBL1764312 | 0.80 | SIRT5 (0.51) | DPP4DPP8DPP9BMP1TASP1 | |
| SCHEMBL1682360 | 0.79 | ALDH1A1 (0.43) | DPP4DPP8DPP9BMP1TASP1 | |
| SCHEMBL1764514 | 0.79 | GNPAT (0.54) | BMP1TASP1SIRT5ALDH1A1GNPAT | |
| SCHEMBL7947817 | 0.79 | DPP8 (0.61) | DPP4DPP8DPP9BMP1ALOX15 | |
| SCHEMBL1764511 | 0.79 | GNPAT (0.54) | BMP1TASP1SIRT5ALDH1A1GNPAT | |
| SCHEMBL7947818 | 0.79 | DPP8 (0.61) | DPP4DPP8DPP9BMP1ALOX15 | |
| SCHEMBL11933753 | 0.78 | BMP1 (0.55) | DPP4DPP8DPP9BMP1SIRT5 | |
| SCHEMBL17849546 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GNPATSIRT6SIRT1KDM4E | |
| SCHEMBL7857411 | 0.76 | TASP1 (0.43) | DPP4DPP8DPP9BMP1TASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061590-A1 | CYTOTOXIC AGENTS COMPRISING NEW ANSAMITOCIN DERIVATIVES | IMMUNOGEN, INC. (US) | 2012-05-10 | — | — | WO | disclosed |