Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122563 | 0.88 | PCSK9 (0.33) | HRH4ACLY | |
| SCHEMBL3204654 | 0.88 | HRH4 (0.33) | HRH4ACLYPDE4A | |
| SCHEMBL3194668 | 0.87 | RORC (0.35) | HRH4ACLY | |
| SCHEMBL3214943 | 0.87 | HRH4 (0.33) | HRH4ACLY | |
| SCHEMBL3202779 | 0.87 | LMNA (0.38) | HRH4ACLY | |
| SCHEMBL3208426 | 0.86 | ACLY (0.34) | HRH4ACLYPDE4A | |
| SCHEMBL3212622 | 0.86 | PDE4A (0.33) | HRH4ACLYPDE4A | |
| SCHEMBL3213223 | 0.83 | HRH4 (0.31) | HRH4ACLY | |
| SCHEMBL3211858 | 0.82 | HRH4 (0.40) | HRH4PDE4A | |
| SCHEMBL3207210 | 0.82 | TAAR1 (0.43) | HRH4ACLYPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |