Styrene

SCHEMBL7948135

C=C(CCCC)C(=O)O.C=CC(=O)O.C=Cc1ccc(S(=O)(=O)O)cc1.C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	TDP1	Q9NUW8	2/20	0.50

▸	CES2	O00748	2/20	0.37

▸	CES1	P23141	2/20	0.37

▸	LMNA	P02545	1/20	0.36

▸	PTGS2	P35354	2/20	0.36

▸	TSHR	P16473	2/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.35

▸	MCL1	Q07820	1/20	0.34

▸	ALDH1A1	P00352	2/20	0.34

▸	EGFR	P00533	1/20	0.34

▸	HDAC3	O15379	1/20	0.34

▸	GAA	P10253	1/20	0.34

▸	HPGD	P15428	1/20	0.34

▸	S1PR3	Q99500	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Styrene SCHEMBL987788	0.89	LMNA (0.44)	TDP1CES2CES1LMNAPTGS2
Styrene SCHEMBL7948253	0.88	TDP1 (0.50)	TDP1CES2CES1LMNAPTGS2
Styrene SCHEMBL8862982	0.85	LMNA (0.41)	TDP1CES2CES1LMNATSHR
Styrene SCHEMBL8862498	0.85	LMNA (0.41)	TDP1CES2CES1LMNATSHR
Styrene SCHEMBL8471452	0.85	LMNA (0.41)	TDP1CES2CES1LMNATSHR
Styrene SCHEMBL258132	0.84	LMNA (0.47)	TDP1CES2CES1LMNAPTGS2
Styrene SCHEMBL5270544	0.84	LMNA (0.47)	TDP1CES2CES1LMNAPTGS2
Styrene SCHEMBL17065130	0.84	LMNA (0.47)	TDP1CES2CES1LMNAPTGS2
Styrene SCHEMBL7850481	0.83	GAA (0.37)	TDP1CES2CES1LMNAEGFR
Styrene SCHEMBL3430856	0.81	LMNA (0.39)	TDP1CES2CES1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6190820-B1	Toner processes	XEROX CORPORATION	2001-02-20	—	—	US	disclosed