Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.35 |
| ▸ | TYMP | P19971 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958047 | 0.92 | NT5E (0.38) | NT5EHPSELGALS8TYMPALDH1A1 | |
| SCHEMBL7948338 | 0.90 | NT5E (0.39) | NT5EHPSETYMPALDH1A1CYP2C9 | |
| SCHEMBL7958046 | 0.89 | NT5E (0.44) | NT5EHPSELGALS8TYMPALDH1A1 | |
| SCHEMBL7957807 | 0.89 | TYMP (0.38) | NT5EHPSELGALS8TYMPALDH1A1 | |
| SCHEMBL7955443 | 0.86 | NT5E (0.50) | NT5EHPSETYMP | |
| SCHEMBL7955444 | 0.86 | NT5E (0.50) | NT5EHPSETYMP | |
| SCHEMBL7958643 | 0.84 | LGALS8 (0.45) | PTGS2LGALS8ALDH1A1 | |
| SCHEMBL8316403 | 0.84 | LGALS8 (0.45) | PTGS2LGALS8ALDH1A1 | |
| SCHEMBL7962368 | 0.84 | TYR (0.42) | NT5EHPSETYMPALDH1A1 | |
| SCHEMBL7962363 | 0.84 | TYR (0.42) | NT5EHPSETYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |