SCHEMBL7948225

SCHEMBL7948225

O=C(O)C=Cc1ccc(NC(=O)c2ccc(F)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.64
SNCA P37840 3/20 0.62
RAB9A P51151 3/20 0.61
NPC1 O15118 2/20 0.61
PTPN1 P18031 1/20 0.61
MEN1 O00255 2/20 0.59
POLB P06746 2/20 0.59
KMT2A Q03164 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
MMP1 P03956 2/20 0.57
MMP2 P08253 2/20 0.57
MMP9 P14780 2/20 0.57
EGFR P00533 1/20 0.57
USP2 O75604 1/20 0.57
MAOB P27338 1/20 0.56
MET P08581 2/20 0.55
PTGS2 P35354 2/20 0.55
ATM Q13315 1/20 0.55
TNFRSF1A P19438 1/20 0.54
PKM P14618 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233005 0.86 PKM (0.70) RAB9ANPC1PTPN1MEN1POLB
SCHEMBL1233002 0.86 PKM (0.70) RAB9ANPC1PTPN1MEN1POLB
SCHEMBL12425742 0.86 PKM (0.70) RAB9ANPC1PTPN1MEN1POLB
SCHEMBL5583041 0.84 PTPN1 (0.64) PTPN1MEN1POLBKMT2APKM
SCHEMBL5583040 0.84 PTPN1 (0.64) PTPN1MEN1POLBKMT2APKM
SCHEMBL6965101 0.82 GAA (0.67) SNCARAB9AMEN1POLBKMT2A
SCHEMBL6969345 0.82 KDM4E (0.67) SNCARAB9AMEN1POLBKMT2A
SCHEMBL6965107 0.82 GAA (0.67) SNCARAB9AMEN1POLBKMT2A
SCHEMBL7005530 0.82 KDM4E (0.67) SNCARAB9AMEN1POLBKMT2A
SCHEMBL81378 0.82 HSD11B1 (0.72) PTPN1MEN1POLBKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6174649-B1 THERMOSTABILITY AND PHOTOELECTRIC CHARACTERISTICS SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 2001-01-16 US disclosed