Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | IL2 | P60568 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939066 | 0.83 | RAB9A (0.46) | RAB9AMAPTGAANPSR1CYP3A4 | |
| SCHEMBL7947680 | 0.80 | IL2 (0.54) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL6811539 | 0.80 | MAPT (0.52) | RAB9AMAPTGAANPSR1CYP3A4 | |
| SCHEMBL6811545 | 0.75 | CYP3A4 (0.47) | RAB9AMAPTGAANPSR1CYP3A4 | |
| SCHEMBL7950537 | 0.71 | POLB (0.50) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL7938910 | 0.70 | KMT2A (0.47) | RAB9AMAPTGAAMEN1KMT2A | |
| SCHEMBL7601717 | 0.69 | KMT2A (0.45) | RAB9AMAPTMEN1KMT2AJAK2 | |
| SCHEMBL30499704 | 0.69 | KMT2A (0.45) | RAB9AMAPTMEN1KMT2AJAK2 | |
| SCHEMBL24869590 | 0.68 | ALDH1A1 (0.53) | MAPTNPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7947411 | 0.67 | NPC1 (0.46) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |