Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948340 | 0.80 | RAB9A (0.47) | IL2TLR7ITGB1ITGA4NPSR1 | |
| SCHEMBL6815920 | 0.80 | IL2 (0.58) | IL2KDRTLR7TLR8NPSR1 | |
| SCHEMBL11619037 | 0.79 | KDR (0.66) | IL2KDRNPSR1GAAMAPT | |
| SCHEMBL7939066 | 0.79 | RAB9A (0.46) | IL2TLR7ITGB1ITGA4TLR8 | |
| SCHEMBL22339739 | 0.77 | TMPRSS4 (0.59) | IL2KDRTLR7TLR8NPSR1 | |
| SCHEMBL17144306 | 0.76 | TLR7 (0.57) | IL2KDRTLR7TLR8NPSR1 | |
| SCHEMBL6815923 | 0.74 | IL2 (0.53) | IL2KDRTLR7TLR8NPSR1 | |
| SCHEMBL8559828 | 0.74 | CTSD (0.55) | KDRMAPTRAB9AGRM4TRPV1 | |
| SCHEMBL6819897 | 0.74 | KDR (0.68) | KDRNPSR1MAPTRAB9AGRM4 | |
| SCHEMBL11088680 | 0.73 | KDR (0.56) | IL2KDRNPSR1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |