Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301026 | 0.83 | MAPT (0.51) | L3MBTL1GAATDP1KMT2AMEN1 | |
| SCHEMBL29361524 | 0.78 | MAPT (0.39) | L3MBTL1MAPK1TDP1KMT2AMEN1 | |
| SCHEMBL29176 | 0.78 | MAPT (0.39) | L3MBTL1MAPK1TDP1KMT2AMEN1 | |
| SCHEMBL5107 | 0.77 | ALDH1A1 (0.44) | MAPK1TDP1MAPTKDM4ECYP1A2 | |
| SCHEMBL29350037 | 0.77 | ALDH1A1 (0.44) | MAPK1TDP1MAPTKDM4ECYP1A2 | |
| SCHEMBL10323632 | 0.77 | ALDH1A1 (0.44) | MAPK1TDP1MAPTKDM4ECYP1A2 | |
| SCHEMBL29496111 | 0.77 | ALDH1A1 (0.44) | MAPK1TDP1MAPTKDM4ECYP1A2 | |
| SCHEMBL146878 | 0.77 | ALDH1A1 (0.44) | MAPK1TDP1MAPTKDM4ECYP1A2 | |
| SCHEMBL2390135 | 0.77 | MAPT (0.36) | L3MBTL1GAATDP1MAPTALOX5 | |
| SCHEMBL635229 | 0.77 | MEN1 (0.42) | L3MBTL1GAAMAPK1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184415-B1 | ASYMMETRIC HYDROGENATION OF A 2-HALO(ELECTRONEGATIVE)ALKENOIC ACID/SALT (2-HALOACRYLIC ACID OR SALT), USING AN ENANTIOMETRICAL RICHED CATALYST OF 2,2'-BIS(DIARYLPHOSPHINO-PHINO-1,1'-BINAPHTHYL COMPLEX OF RUTHENIUM; HALIDE PROMOTERS | ALBEMARLE CORPORATION | 2001-02-06 | — | — | US | disclosed |