Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750389 | 0.91 | ESR1 (0.57) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL30010731 | 0.85 | LMNA (0.50) | HPGDTSHRHSD17B10PTPN5ALDH1A1 | |
| SCHEMBL18282984 | 0.85 | LMNA (0.50) | HPGDTSHRHSD17B10PTPN5ALDH1A1 | |
| SCHEMBL2644008 | 0.85 | LMNA (0.50) | HPGDTSHRHSD17B10PTPN5ALDH1A1 | |
| SCHEMBL31201776 | 0.83 | PTPN5 (0.46) | PTPN5ALDH1A1NOS3NOS1UGT2B7 | |
| SCHEMBL18290606 | 0.81 | PTPN5 (0.53) | PTPN5ALDH1A1NOS3NOS1UGT2B7 | |
| SCHEMBL30521586 | 0.81 | PTPN5 (0.53) | ESR1ESR2PTPN5ALDH1A1NOS3 | |
| SCHEMBL1332759 | 0.81 | PTPN5 (0.44) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL28637182 | 0.81 | PTPN5 (0.44) | ESR1ESR2CYP3A4ARHPGD | |
| SCHEMBL40655 | 0.81 | NOS3 (0.54) | ESR1ESR2TSHRHSD17B10PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000031584-A2 | LIQUID COMPOSITION POLYMERIZABLE INTO ORGANIC GLASSES WITH A HIGH REFRACTIVE INDEX | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 2000-06-02 | — | — | WO | claimed |
| EP-0473163-B1 | Liquid composition which can polymerize into almost colourless and easily dyeable organic glass | GREAT LAKES CHEMICAL ITALIA (IT) | 1995-11-02 | — | — | EP | claimed |
| US-6274759-B1 | POLYURETHANE FOAMS | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-14 | — | — | US | disclosed |
| WO-2000031584-A2 | LIQUID COMPOSITION POLYMERIZABLE INTO ORGANIC GLASSES WITH A HIGH REFRACTIVE INDEX | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 2000-06-02 | — | — | WO | disclosed |
| EP-0473163-B1 | Liquid composition which can polymerize into almost colourless and easily dyeable organic glass | GREAT LAKES CHEMICAL ITALIA (IT) | 1995-11-02 | — | — | EP | disclosed |
| EP-0473163-A1 | Liquid composition which can polymerize into almost colourless and easily dyeable organic glass | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1992-03-04 | — | — | EP | disclosed |
| US-4067853-A | ABRASION RESISTANT ACRYLIC POLYMERS FOR DENTURES | ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DT) | 1978-01-10 | — | — | US | disclosed |