SCHEMBL7948399

SCHEMBL7948399

COC(=O)C(C)c1ccc(C)c(C)c1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MT-CO2 P00403 1/20 0.59
PTGS1 P23219 2/20 0.51
PTGS2 P35354 2/20 0.51
TSHR P16473 1/20 0.50
RECQL P46063 1/20 0.50
TAS1R3 Q7RTX0 1/20 0.50
TAS1R1 Q7RTX1 1/20 0.50
HPGD P15428 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
AKR1C3 P42330 2/20 0.43
AKR1C2 P52895 2/20 0.43
TP53 P04637 1/20 0.43
CDC42 P60953 1/20 0.40
RAC1 P63000 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19392984 0.84 MT-CO2 (0.55) MT-CO2PTGS1PTGS2AKR1C3AKR1C2
SCHEMBL7098148 0.84 MT-CO2 (0.55) MT-CO2PTGS1PTGS2HPGDTDP1
SCHEMBL9063569 0.84 MT-CO2 (0.55) MT-CO2PTGS1PTGS2HPGDAKR1C3
SCHEMBL16865531 0.84 MT-CO2 (0.55) MT-CO2PTGS1PTGS2TAS1R3TAS1R1
SCHEMBL4062797 0.83 ALDH1A1 (0.49) MT-CO2TSHRRECQLTAS1R3TAS1R1
SCHEMBL14420090 0.83 MT-CO2 (0.54) MT-CO2PTGS1PTGS2TSHRRECQL
SCHEMBL27711084 0.80 TDP1 (0.44) MT-CO2PTGS1PTGS2HPGDTDP1
SCHEMBL14032432 0.80 TSHR (0.45) MT-CO2TSHRRECQLTAS1R3TAS1R1
SCHEMBL12607235 0.80 TSHR (0.45) MT-CO2TSHRRECQLTAS1R3TAS1R1
SCHEMBL14264293 0.79 MT-CO2 (0.56) MT-CO2PTGS1PTGS2TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6251833-B1 PESTICIDE; HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 2001-06-26 US disclosed