Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL850725 | 0.85 | ALDH1A1 (0.45) | MT-CO2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL7948399 | 0.84 | MT-CO2 (0.59) | MT-CO2PTGS1PTGS2HPGDTDP1 | |
| SCHEMBL27463420 | 0.83 | APP (0.49) | MT-CO2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL28791672 | 0.82 | CHRNA1 (0.44) | MT-CO2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL17891802 | 0.82 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2SLC6A2SLC6A4 | |
| SCHEMBL8321208 | 0.82 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2MAPTHPGD | |
| SCHEMBL5485178 | 0.82 | ALDH1A1 (0.43) | MT-CO2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL1679001 | 0.81 | AKR1C3 (0.53) | PTGS1PTGS2AKR1C3AKR1C2KMT2A | |
| SCHEMBL31614294 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS1PTGS2HPGDTDP1 | |
| SCHEMBL27640937 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS1PTGS2HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6451843-B1 | Arylphenyl-substituted cyclic keto enols | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, SULT1E1 | MT-CO2 646/4885PTGS1 498/4885PTGS2 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.