Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435579 | 0.84 | TSHR (0.61) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL2884550 | 0.84 | ALDH1A1 (0.55) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL7946320 | 0.83 | ALDH1A1 (0.44) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL578128 | 0.81 | TSHR (0.77) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL2825239 | 0.80 | TSHR (0.69) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL6227956 | 0.79 | TSHR (0.53) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL7669334 | 0.78 | TSHR (0.71) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL7670783 | 0.78 | TSHR (0.71) | TSHRHSD17B10ALDH1A1KDM4ECDC25B | |
| Diethyl Phthalate SCHEMBL27896497 | 0.78 | TSHR (0.84) | TSHRHSD17B10ALDH1A1KMT2ALMNA | |
| SCHEMBL1492404 | 0.78 | TSHR (0.65) | TSHRHSD17B10ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6222060-B1 | REACTING LACTONE COMPOUND WITH THIONYL CHLORIDE; ESTERIFYING WITH ALCOHOL; REACTING WITH SALT OF THIOSULFONIC ACID; CHLORINATING TO PREPARE O-(CARBOALKOXY)PHENYLMETHANESULFONYL CHLORIDE DERIVATIVE | KOREAN RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-04-24 | — | — | US | disclosed |
| WO-1999016743-A1 | A PROCESS FOR PREPARING o-(CARBOALKOXY) PHENYLMETHANESULFONYL CHLORIDE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-04-08 | — | — | WO | disclosed |