Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15461583 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL7363401 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL7948405 | 0.84 | TSHR (0.61) | ALDH1A1LMNATSHRHSD17B10KMT2A | |
| SCHEMBL4880583 | 0.83 | CA1 (0.58) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL646787 | 0.81 | L3MBTL1 (0.54) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL4912518 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL7946320 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRHSD17B10HIF1A | |
| SCHEMBL29539913 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL9513083 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNACA1CA2CA5A | |
| SCHEMBL4784798 | 0.79 | FOLH1 (0.52) | ALDH1A1CA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563236-A | Synthesis method of o-methyl formate benzylsulfonamide | 石家庄圣泰化工有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113563236-A | Synthesis method of o-methyl formate benzylsulfonamide | 石家庄圣泰化工有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-8283373-B2 | Inhibitors of cytosolic phospholipase A2 | PFIZER INC. (US) | 2012-10-09 | — | — | US | disclosed |
| CN-102040550-A | Inhibitors of cytosolic phospholipase A2 | WYETH CORP | 2011-05-04 | — | — | CN | disclosed |
| CN-101184729-B | Cytosolic phospholipase A2Inhibitors | WYETH CORP | 2011-02-16 | — | — | CN | disclosed |
| EP-1891006-B1 | INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | WYETH LLC (US) | 2010-11-24 | — | — | EP | disclosed |
| EP-2248801-A1 | Inhibitors of cytosolic phospholipase a2 | Wyeth LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| US-20100029645-A1 | Inhibitors of Cytosolic Phospholipase A2 | WYETH LLC | 2010-02-04 | — | — | US | disclosed |
| US-20100022536-A1 | Inhibitors of Cytosolic Phospholipase A2 | NOVARTIS AG (CH) | 2010-01-28 | — | — | US | disclosed |
| US-7557135-B2 | Inhibitors of cytosolic phospholipase A2 | WYETH (US) | 2009-07-07 | — | — | US | disclosed |
| EP-0416319-A2 | Process for the preparation of sulfonylisoureas | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |
| EP-0372326-A2 | Sulfonyl amino azines, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1990-06-13 | — | — | EP | disclosed |
| US-4897105-A | (1,2,4)-THIADIAZOLO(2,3-A)PYRIMIDINE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4802910-A | Herbicidal acylated sulphonylguanidines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-07 | — | — | US | disclosed |
| US-4737185-A | Herbicidal 2,6-disubstituted benzylsulfonamides and benzebesulfamates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| CN-87102275-A | Selective herbicide and manufacturing thereof and use | — | 1988-02-17 | — | — | CN | disclosed |
| EP-0239064-A2 | Herbicidal compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-30 | — | — | EP | disclosed |
| EP-0234250-A2 | Acylated sulphonylguanidines | BAYER AG (DE) | 1987-09-02 | — | — | EP | disclosed |
| US-4678500-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0173321-A1 | Sulfonyl-guanidinopyrimidine derivatives | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022536-A1 | Inhibitors of Cytosolic Phospholipase A2 | PLA2G4B, PLA2G4A, PLA2G12A | ALDH1A1 2405/4885LMNA 782/4885CA1 1223/4885 |
| US-20100029645-A1 | Inhibitors of Cytosolic Phospholipase A2 | PLA2G4B, PLA2G4A, PLA2G12A | ALDH1A1 2405/4885LMNA 782/4885CA1 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.