SCHEMBL7948679

SCHEMBL7948679

CCC[C@H](C)CC(=O)CP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 6/20 0.45
METAP1 P53582 2/20 0.42
TSHR P16473 2/20 0.38
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
BLM P54132 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LAP3 P28838 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547924 0.89 FDPS (0.48) FDPSMETAP1LAP3
SCHEMBL3737096 0.89 FDPS (0.48) FDPSMETAP1LAP3
SCHEMBL3741705 0.85 FDPS (0.52) FDPSLAP3
SCHEMBL2990948 0.82 FDPS (0.46) FDPSMETAP1TSHRMEN1LMNA
SCHEMBL958472 0.81 BLM (0.44) FDPSTSHRMEN1LMNAHPGD
SCHEMBL11559831 0.80 TSHR (0.50) FDPSMETAP1TSHRTDP1CYP2C19
SCHEMBL959452 0.79 LMNA (0.40) FDPSLMNABLMTDP1LAP3
SCHEMBL7948595 0.79 TSHR (0.34) FDPSMETAP1TSHR
SCHEMBL9254795 0.79 TSHR (0.34) FDPSMETAP1TSHR
SCHEMBL10335377 0.78 GRIN2D (0.34) FDPSTSHRMEN1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265440-B1 STOMACH ULCERS R-TECH UENO, LTD. (JP) 2001-07-24 US disclosed
US-5886034-A ANTIULCER AGENTS KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) 1999-03-23 US disclosed
US-5770759-A 13,14-DIHYDRO-15-KETO-PGF'S; VASOPRESSORS R-TECH UENO, LTD. (JP) 1998-06-23 US disclosed
US-5591887-A 13,14-DIHYDRO-15-KETO-PGFS R-TECH UENO, LTD. (JP) 1997-01-07 US disclosed
US-5428062-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1995-06-27 US disclosed
US-5380709-A Prostaglandins E and anti ulcers containing same K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1995-01-10 US disclosed
US-5284858-A Prostaglandins E and anti ulcers containing same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1994-02-08 US disclosed
US-5225439-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1993-07-06 US disclosed
US-5221763-A 13,14-dihydro-15-keto-PGFs and salts R-TECH UENO, LTD. (JP) 1993-06-22 US disclosed
US-5166174-A For duodenal ulcers or gastric ulcers K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-11-24 US disclosed
EP-0284180-B1 PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-08-19 EP disclosed
US-5106869-A Vasopressor activity without ephemeral vasorelaxation; no effect on trachea, intestine K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-04-21 US disclosed
EP-0289349-B1 PROSTAGLANDINS OF THE F SERIES Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-01-29 EP disclosed
EP-0289349-A1 Prostaglandins of the F series Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-11-02 EP disclosed
US-4775692-A ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT TORAY INDUSTRIES, INC. (JP) 1988-10-04 US disclosed
EP-0284180-A1 Prostaglandins E and anti ulcers containing same Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-09-28 EP disclosed