SCHEMBL959452

SCHEMBL959452

CC(C)CCCCC[C@H](C)CC(=O)CP(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
BLM P54132 1/20 0.39
FDPS P14324 4/20 0.36
LAP3 P28838 1/20 0.34
ACE2 Q9BYF1 1/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM4A O75164 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL958472 0.95 BLM (0.44) LMNABLMFDPSLAP3ALDH1A1
SCHEMBL3741705 0.88 FDPS (0.52) FDPSLAP3ACE2
SCHEMBL9547924 0.84 FDPS (0.48) FDPSLAP3ACE2
SCHEMBL3737096 0.84 FDPS (0.48) FDPSLAP3ACE2
SCHEMBL7950976 0.81 KDM4C (0.41) FDPSLAP3KDM4CKDM4APHF8
SCHEMBL7570633 0.81 KDM4C (0.41) FDPSLAP3KDM4CKDM4APHF8
SCHEMBL7947910 0.81 KDM4C (0.41) FDPSLAP3KDM4CKDM4APHF8
SCHEMBL2302042 0.81 KDM4C (0.41) FDPSLAP3KDM4CKDM4APHF8
SCHEMBL2304432 0.79 KDM4C (0.39) LMNABLMFDPSLAP3KDM4C
SCHEMBL7948679 0.79 FDPS (0.45) LMNABLMFDPSLAP3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110015238-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES ONO PHARMACEUTICAL CO., LTD. (JP) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015238-A1 BLOOD FLOW PROMOTERS FOR CAUDA EQUINA TISSUES PTGFR, PTGIS, PTGIR LMNA 1814/4885BLM 4806/4885FDPS 1580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.