Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 17/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.30 |
| ▸ | CDK9 | P50750 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017328 | 0.75 | PDE10A (0.48) | PDE10ACDK7CDK9 | |
| SCHEMBL1688394 | 0.72 | TYRO3 (0.34) | — | |
| SCHEMBL1294520 | 0.72 | PIN1 (0.44) | PDE10A | |
| SCHEMBL16838271 | 0.72 | PDE10A (0.55) | PDE10A | |
| SCHEMBL8400864 | 0.69 | — | — | |
| SCHEMBL12476433 | 0.69 | MAPT (0.41) | — | |
| SCHEMBL30283284 | 0.68 | PDE10A (0.41) | PDE10A | |
| SCHEMBL26234898 | 0.68 | PDE10A (0.41) | PDE10A | |
| SCHEMBL30829012 | 0.68 | PDE10A (0.46) | PDE10A | |
| SCHEMBL3826088 | 0.67 | PDE10A (0.39) | PDE10ACDK7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364313-B1 | AZA-BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2014-01-08 | — | — | EP | disclosed |
| WO-2010030500-A1 | AZA-BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-18 | — | — | WO | disclosed |