Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.53 |
| ▸ | CREB1 | P16220 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7548423 | 0.87 | PPARG (0.63) | PPARGADORA3CREB1ABCB1BCHE | |
| SCHEMBL1483627 | 0.86 | PPARG (0.67) | PPARGADORA3CREB1ABCB1BCHE | |
| SCHEMBL3982524 | 0.85 | PPARG (0.67) | PPARGADORA3CREB1ABCB1BCHE | |
| SCHEMBL31031155 | 0.85 | PPARG (0.78) | PPARGADORA3CREB1ABCB1L3MBTL1 | |
| SCHEMBL7551823 | 0.82 | PPARG (0.92) | PPARGADORA3ABCB1L3MBTL1KDM4E | |
| SCHEMBL16151312 | 0.81 | PPARG (0.71) | PPARGADORA3ABCB1L3MBTL1MAPT | |
| SCHEMBL1422056 | 0.81 | PPARG (0.53) | PPARGADORA3L3MBTL1BCHEACHE | |
| SCHEMBL7554074 | 0.81 | PPARG (0.64) | PPARGADORA3ABCB1KDM4EMAPT | |
| SCHEMBL31031138 | 0.81 | ADORA3 (0.75) | PPARGADORA3CREB1ABCB1BCHE | |
| SCHEMBL30375357 | 0.80 | PPARG (0.77) | PPARGADORA3ABCB1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258840-B1 | ANTITUMOR AGENTS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF KINASES | COBRA THERAPEUTICS LIMITED (GB) | 2001-07-10 | — | — | US | disclosed |