Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CREB1 | P16220 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554074 | 0.93 | PPARG (0.64) | PPARGADORA3KDM4EABCG2EDNRA | |
| SCHEMBL7549118 | 0.88 | PPARG (0.54) | PPARGADORA3ABCG2KCNA3EDNRA | |
| SCHEMBL1483627 | 0.88 | PPARG (0.67) | PPARGADORA3KDM4EGAAABCG2 | |
| SCHEMBL7948858 | 0.87 | PPARG (0.67) | PPARGADORA3KDM4EGAAABCG2 | |
| SCHEMBL1664326 | 0.83 | ADORA3 (0.70) | PPARGADORA3KDM4EGAAABCG2 | |
| SCHEMBL3982524 | 0.83 | PPARG (0.67) | PPARGADORA3KDM4EKMT2AMAOB | |
| SCHEMBL31031155 | 0.83 | PPARG (0.78) | PPARGADORA3CREB1ABCB1 | |
| SCHEMBL15270283 | 0.82 | PPARG (0.44) | PPARGEDNRAMAOBCREB1BCHE | |
| SCHEMBL30375357 | 0.82 | PPARG (0.77) | PPARGADORA3KDM4EGAAABCG2 | |
| SCHEMBL16151329 | 0.81 | PPARG (0.62) | PPARGADORA3KDM4EABCG2KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481919-A | Flavone glycoside derivatives, and preparation method and application thereof | GUIZHOU BAILING GROUP PHARMACEUTICAL CO LTD | 2016-04-13 | — | — | CN | disclosed |
| EP-1214308-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021608-A2 | NOVEL FLAVONOIDS | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 2001-03-29 | — | — | WO | disclosed |