Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419727 | 0.95 | — | — | |
| SCHEMBL4266980 | 0.89 | — | — | |
| SCHEMBL9418128 | 0.86 | — | — | |
| SCHEMBL1119349 | 0.84 | — | — | |
| SCHEMBL2839051 | 0.84 | — | — | |
| SCHEMBL5246570 | 0.84 | — | — | |
| SCHEMBL3180780 | 0.84 | — | — | |
| SCHEMBL12476942 | 0.84 | — | — | |
| Lithium Ion SCHEMBL43386 | 0.84 | — | — | |
| SCHEMBL11745139 | 0.84 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255419-B1 | POLYMERIZING OR COPOLYMERIZING OLEFINS IN PRESENCE OF POLYMERIZATION CATALYST COMPRISING TRANSITION METAL AMIDE COMPOUND, ORGANOALUMINUM OXY-COMPOUND ADDED TO SYSTEM AS ALIPHATIC OR ALICYCLIC HYDROCARBON SLURRY | MITSUI CHEMICALS, INC. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0893454-A1 | OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS | Mitsui Chemicals, Inc. (JP) | 1999-01-27 | — | — | EP | disclosed |