Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.41 |
| ▸ | RXRB | P28702 | 4/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | RARG | P13631 | 5/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483500 | 0.83 | RXRA (0.42) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL9484572 | 0.83 | POLB (0.52) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL9626066 | 0.77 | RXRA (0.46) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL9506936 | 0.75 | POLB (0.38) | RXRAHNF4APOLBTDP1 | |
| SCHEMBL6144255 | 0.73 | CYP26A1 (0.54) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL5665343 | 0.71 | POLB (0.46) | CYP3A4POLBGAATDP1GLA | |
| SCHEMBL9379226 | 0.71 | KMT2A (0.51) | POLBGAA | |
| SCHEMBL11249732 | 0.71 | LMNA (0.51) | POLBGAA | |
| SCHEMBL8839324 | 0.69 | RXRA (0.53) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL23446783 | 0.68 | PPARG (0.47) | RXRARXRBCYP26A1CYP3A4CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326900-A | Aromatic keto compounds, the preparation thereof, and drugs and cosmetics containing these | BASF AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |
| US-5194664-A | Aromatic keto compounds, the preparation thereof, and drugs and cosmetics containing these | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |