Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | CCR1 | P32246 | 12/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960233 | 0.89 | CCR1 (0.54) | DRD2CCR1ADRA1A | |
| SCHEMBL7949619 | 0.89 | DRD2 (0.53) | DRD2CCR1ADRA1A | |
| SCHEMBL7949042 | 0.88 | CCR1 (0.52) | DRD2CCR1 | |
| SCHEMBL7957164 | 0.87 | DRD2 (0.56) | DRD2CCR1 | |
| SCHEMBL7957456 | 0.86 | CCR1 (0.56) | DRD2CCR1ADRA1A | |
| SCHEMBL7963903 | 0.85 | DRD2 (0.50) | DRD2CCR1 | |
| SCHEMBL7961470 | 0.83 | DRD2 (0.49) | DRD2CCR1 | |
| SCHEMBL7964042 | 0.83 | DRD2 (0.46) | DRD2CCR1 | |
| SCHEMBL8568579 | 0.83 | OPRM1 (0.58) | DRD2CCR1 | |
| SCHEMBL7963515 | 0.83 | CCR1 (0.58) | DRD2CCR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |