Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | LYN | P07948 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.41 |
| ▸ | MARK3 | P27448 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | BLK | P51451 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.41 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193541 | 0.81 | BCL6 (0.58) | BCL6AURKAMAPTCDK2PIM1 | |
| SCHEMBL796547 | 0.79 | NPC1 (0.50) | BCL6MAPTRAB9AMAPK1NPC1 | |
| SCHEMBL796545 | 0.79 | NPC1 (0.50) | BCL6MAPTRAB9AMAPK1NPC1 | |
| SCHEMBL824411 | 0.76 | BCL6 (0.74) | BCL6AURKAMAPTCDK2PIM1 | |
| SCHEMBL8908340 | 0.72 | GAA (0.71) | BCL6AURKAMAPTCDK2PIM1 | |
| SCHEMBL5137042 | 0.72 | BCL6 (0.62) | BCL6AURKAMAPTCDK2PIM1 | |
| Amanozine SCHEMBL689928 | 0.72 | BCL6 (1.00) | BCL6AURKAMAPTCDK2PIM1 | |
| Amanozine SCHEMBL30264199 | 0.72 | BCL6 (1.00) | BCL6AURKAMAPTCDK2PIM1 | |
| SCHEMBL14972606 | 0.70 | BCL6 (0.71) | BCL6AURKAMAPTCDK2PIM1 | |
| Amanozine SCHEMBL2490900 | 0.70 | BCL6 (0.96) | BCL6AURKAMAPTCDK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-A1 | TRIAZINE-OXADIAZOLES | Novartis AG (CH) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |