Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7881676 | 0.78 | ENPP2 (0.48) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL13140628 | 0.75 | ACHE (0.35) | — | |
| SCHEMBL9289 | 0.75 | TSHR (0.61) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL2817154 | 0.75 | TSHR (0.61) | ENPP2TSHRCLK4GSK3BDRD2 | |
| Water SCHEMBL28137572 | 0.75 | TSHR (0.61) | ENPP2TSHRCLK4GSK3BDRD2 | |
| Hydrochloric Acid SCHEMBL19327577 | 0.73 | TSHR (0.58) | ENPP2TSHRCLK4GSK3BDRD2 | |
| Fluoride SCHEMBL28362409 | 0.73 | TSHR (0.58) | ENPP2TSHRCLK4GSK3BDRD2 | |
| Ammonia Solution, Strong SCHEMBL27601226 | 0.73 | TSHR (0.58) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL27977620 | 0.73 | TSHR (0.58) | ENPP2TSHRCLK4GSK3BDRD2 | |
| SCHEMBL12775181 | 0.72 | CYP2A6 (0.52) | ENPP2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925958-A1 | COMPOUND HAVING BENZAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2021-12-22 | — | — | EP | disclosed |
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |