Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950942 | 0.90 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KDM4EHSD17B10KMT2A | |
| SCHEMBL7962214 | 0.87 | ALDH1A1 (0.46) | ALDH1A1ADORA2BL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL7951054 | 0.85 | CYP1A2 (0.43) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL7961174 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ADORA2BL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL7293735 | 0.78 | KDM4E (0.54) | ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7293146 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ADORA2BL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL7959205 | 0.77 | ALDH1A1 (0.49) | ALDH1A1ADORA2BL3MBTL1KDM4ELMNA | |
| SCHEMBL7965013 | 0.76 | HSD17B10 (0.37) | ALDH1A1ADORA2BKDM4ELMNASMN1; SMN2 | |
| SCHEMBL7294277 | 0.74 | ELANE (0.59) | NPC1RAB9A | |
| SCHEMBL7965028 | 0.74 | ALDH1A1 (0.47) | ALDH1A1ADORA2BL3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |