Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962214 | 0.88 | ALDH1A1 (0.46) | HSD17B10KDM4EALDH1A1CYP1A2ADORA2B | |
| SCHEMBL7950942 | 0.87 | ALDH1A1 (0.38) | HSD17B10KDM4EBRD4ALDH1A1CYP1A2 | |
| SCHEMBL7965688 | 0.82 | KDM4E (0.45) | HSD17B10KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL7965891 | 0.78 | KCNA5 (0.41) | HSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7950863 | 0.76 | ALDH1A1 (0.42) | HSD17B10KDM4EALDH1A1ADORA2BHPGD | |
| SCHEMBL7959390 | 0.75 | KDM4E (0.55) | HSD17B10KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL7474272 | 0.74 | KMT2A (0.38) | HSD17B10KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL7963037 | 0.73 | ELANE (0.48) | KDM4EALDH1A1LMNACASP1SMN1; SMN2 | |
| SCHEMBL7961174 | 0.72 | ALDH1A1 (0.45) | HSD17B10KDM4EALDH1A1CYP1A2ADORA2B | |
| SCHEMBL6085892 | 0.71 | ELANE (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |