Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245417 | 0.87 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL226802 | 0.81 | CRHR1 (0.77) | CRHR1 | |
| SCHEMBL7554726 | 0.81 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7557259 | 0.79 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL7554871 | 0.78 | CRHR1 (0.69) | CRHR1 | |
| SCHEMBL7563114 | 0.77 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL7783163 | 0.76 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL7960908 | 0.76 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL7559415 | 0.70 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL7557848 | 0.69 | CRHR1 (0.60) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284766-B1 | DIAGNOSIS, THERAPY OF STRESS DISORDERS | NEUROGEN CORPORATION | 2001-09-04 | — | — | US | disclosed |