Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 15/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554871 | 0.88 | CRHR1 (0.69) | CRHR1TDP1FPR3TSPOTMEM97 | |
| SCHEMBL226802 | 0.88 | CRHR1 (0.77) | CRHR1TDP1FPR3TSPOTMEM97 | |
| SCHEMBL7557259 | 0.86 | CRHR1 (0.66) | CRHR1TDP1FPR3TSPOTMEM97 | |
| SCHEMBL7554726 | 0.85 | CRHR1 (0.64) | CRHR1TDP1 | |
| SCHEMBL7563114 | 0.85 | CRHR1 (0.62) | CRHR1TDP1FPR3TSPOTMEM97 | |
| SCHEMBL245417 | 0.79 | CRHR1 (0.56) | CRHR1TDP1 | |
| SCHEMBL7559415 | 0.77 | CRHR1 (0.70) | CRHR1TDP1 | |
| SCHEMBL7951086 | 0.76 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL7557848 | 0.75 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL7553858 | 0.75 | CRHR1 (0.64) | CRHR1TDP1FPR3TSPOTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284766-B1 | DIAGNOSIS, THERAPY OF STRESS DISORDERS | NEUROGEN CORPORATION | 2001-09-04 | — | — | US | disclosed |