Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 8/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1950495 | 0.72 | MEN1 (0.49) | GLSNFKB1NFKB2RELAMEN1 | |
| SCHEMBL7955760 | 0.72 | KMT2A (0.43) | GLSNFKB1NFKB2RELAHDAC3 | |
| SCHEMBL7951000 | 0.71 | NFKB1 (0.42) | GLSNFKB1NFKB2RELAHDAC3 | |
| SCHEMBL7950069 | 0.70 | NFKB1 (0.42) | GLSNFKB1NFKB2RELAHDAC3 | |
| SCHEMBL7945422 | 0.68 | NFKB1 (0.41) | GLSNFKB1NFKB2RELAMEN1 | |
| SCHEMBL1950210 | 0.64 | ANO1 (0.55) | GLS | |
| SCHEMBL1954085 | 0.61 | ANO1 (0.53) | GLSMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12271221 | 0.61 | MEN1 (0.56) | GLSMEN1KMT2ARAB9ALMNA | |
| SCHEMBL12271719 | 0.61 | ANO1 (0.57) | MEN1KMT2A | |
| SCHEMBL1954594 | 0.60 | ANO1 (0.53) | MEN1KMT2ARAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025295-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-04 | — | — | WO | disclosed |