Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 3/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951761 | 1.00 | PKM (0.35) | PKMP2RX3DPP4IDO1TDO2 | |
| SCHEMBL7955801 | 0.90 | APP (0.33) | PPOXALDH1A1 | |
| SCHEMBL7955799 | 0.90 | APP (0.33) | PPOXALDH1A1 | |
| SCHEMBL7951701 | 0.88 | XPO1 (0.33) | RECQLSMN1; SMN2MAPTCA12CA1 | |
| SCHEMBL7951700 | 0.88 | XPO1 (0.33) | RECQLSMN1; SMN2MAPTCA12CA1 | |
| SCHEMBL10698389 | 0.86 | CYP1A2 (0.33) | SMN1; SMN2 | |
| SCHEMBL30739483 | 0.84 | PPOX (0.38) | PPOX | |
| SCHEMBL27195493 | 0.84 | PPOX (0.38) | PPOX | |
| SCHEMBL30739481 | 0.84 | PPOX (0.38) | PPOX | |
| SCHEMBL6336900 | 0.81 | BAZ2B (0.46) | PKMSMN1; SMN2ALDH1A1MAPTBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207830-B1 | REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE | SYNGENTA CROP PROTECTION, INC. | 2001-03-27 | — | — | US | claimed |
| EP-0831091-A2 | Process for the production of 3-aryl-uracils | Novartis AG (CH) | 1998-03-25 | — | — | EP | claimed |
| US-6207830-B1 | REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE | SYNGENTA CROP PROTECTION, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-0831091-A2 | Process for the production of 3-aryl-uracils | Novartis AG (CH) | 1998-03-25 | — | — | EP | disclosed |