Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955799 | 1.00 | APP (0.33) | APPPPOXALDH1A1 | |
| SCHEMBL7951761 | 0.90 | PKM (0.35) | PPOXALDH1A1 | |
| SCHEMBL7951759 | 0.90 | PKM (0.35) | PPOXALDH1A1 | |
| SCHEMBL7951701 | 0.87 | XPO1 (0.33) | — | |
| SCHEMBL7951700 | 0.87 | XPO1 (0.33) | — | |
| SCHEMBL10698389 | 0.84 | CYP1A2 (0.33) | — | |
| SCHEMBL8543133 | 0.79 | PPOX (0.46) | PPOX | |
| SCHEMBL25359513 | 0.78 | — | — | |
| SCHEMBL7718512 | 0.78 | PPOX (0.30) | PPOX | |
| SCHEMBL30084589 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207830-B1 | REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE | SYNGENTA CROP PROTECTION, INC. | 2001-03-27 | — | — | US | claimed |
| EP-0831091-A2 | Process for the production of 3-aryl-uracils | Novartis AG (CH) | 1998-03-25 | — | — | EP | claimed |
| US-6207830-B1 | REACTING AN ISOCYANATE WITH AN ENAMINE IN PRESENCE OF A BASE | SYNGENTA CROP PROTECTION, INC. | 2001-03-27 | — | — | US | disclosed |
| EP-0831091-A2 | Process for the production of 3-aryl-uracils | Novartis AG (CH) | 1998-03-25 | — | — | EP | disclosed |