Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950913 | 0.85 | ALDH1A1 (0.49) | — | |
| SCHEMBL1772580 | 0.85 | SMN1; SMN2 (0.54) | — | |
| SCHEMBL7952916 | 0.84 | MAOB (0.52) | — | |
| SCHEMBL27499329 | 0.83 | KDM4E (0.56) | — | |
| SCHEMBL27499330 | 0.82 | EDNRB (0.55) | EDNRB | |
| SCHEMBL7943851 | 0.75 | EDNRB (0.76) | EDNRBEDNRA | |
| SCHEMBL7956733 | 0.75 | RAB9A (0.67) | EDNRBEDNRA | |
| SCHEMBL8309784 | 0.74 | EDNRB (0.66) | EDNRBEDNRA | |
| SCHEMBL7956806 | 0.74 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7956965 | 0.73 | EDNRB (0.78) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |