Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.55 |
| ▸ | CA2 | P00918 | 9/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 7/20 | 0.53 |
| ▸ | CA12 | O43570 | 6/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652751 | 1.00 | CA1 (0.55) | CA1CA2HTR6CA9CA12 | |
| SCHEMBL17856468 | 0.98 | CA1 (0.53) | CA1CA2HTR6CA9CA12 | |
| SCHEMBL30437544 | 0.85 | PKM (0.55) | CA1CA2HTR6CA9CA12 | |
| SCHEMBL12719397 | 0.85 | HTR6 (0.70) | HTR6LMNAALDH1A1KDM4EDRD2 | |
| SCHEMBL16966426 | 0.83 | CA1 (0.48) | CA1CA2HTR6CA9CA12 | |
| SCHEMBL4617638 | 0.82 | TSHR (0.53) | CA1CA2HTR6CA9CA12 | |
| Hydrochloric Acid SCHEMBL28784493 | 0.82 | HTR6 (0.54) | HTR6LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL13800992 | 0.82 | DRD2 (0.66) | HTR6ALDH1A1KDM4EMEN1GAA | |
| SCHEMBL38652729 | 0.82 | HTR6 (0.54) | HTR6LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL3125365 | 0.82 | HTR6 (0.54) | HTR6LMNAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002802-A1 | PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |