Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952506 | 1.00 | NFE2L2 (0.52) | NFE2L2NPC1NR1H2NR1H3MAOB | |
| SCHEMBL7952109 | 0.75 | NFE2L2 (0.48) | NFE2L2NPC1NR1H3MAOBMEN1 | |
| SCHEMBL7952104 | 0.75 | NFE2L2 (0.48) | NFE2L2NPC1NR1H3MAOBMEN1 | |
| SCHEMBL12426111 | 0.75 | NFE2L2 (0.47) | NFE2L2 | |
| SCHEMBL6752627 | 0.73 | CYP1A2 (0.44) | NPC1NR1H3MAOBMEN1KMT2A | |
| SCHEMBL6752629 | 0.73 | CYP1A2 (0.44) | NPC1NR1H3MAOBMEN1KMT2A | |
| SCHEMBL7240982 | 0.72 | NFE2L2 (0.58) | NFE2L2NPC1MAOBKMT2AIKBKB | |
| SCHEMBL7951657 | 0.71 | NFE2L2 (0.53) | NFE2L2MAOBMEN1KMT2AMAPK1 | |
| SCHEMBL7951663 | 0.71 | NFE2L2 (0.53) | NFE2L2MAOBMEN1KMT2AMAPK1 | |
| SCHEMBL2234105 | 0.71 | NFE2L2 (1.00) | NFE2L2NPC1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232475-B1 | REACTING A SUBSTITUTED BROMOBENZENE WITH N-VINYLIMIDE; CATALYTIC HYDROGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-1013637-A2 | Process for the preparation of fluor containing phenethylamines and fluor containing beta-iminovinyl- and beta-iminoethylphenyl compounds | Bayer Aktiengesellschaft (DE) | 2000-06-28 | — | — | EP | disclosed |