SCHEMBL7952608

SCHEMBL7952608

Cc1c[c]nc2c(F)cccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.36
ACHE P22303 1/20 0.35
PARP1 P09874 1/20 0.35
PSMD14 O00487 2/20 0.33
COPS5 Q92905 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
PDE7A Q13946 1/20 0.33
PDE7B Q9NP56 1/20 0.33
KDM4E B2RXH2 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDE10A Q9Y233 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3861841 0.82 CYP2A6 (0.42) PARP1PSMD14COPS5CYP1A2CYP2A6
SCHEMBL7954562 0.78 NR4A2 (0.41) ARACHEPARP1PSMD14COPS5
SCHEMBL7954070 0.75 NQO2 (0.42) KDM4EALDH1A1SMN1; SMN2
SCHEMBL5953588 0.75 ELANE (0.35) PSMD14COPS5CYP1A2CYP2A6KDM4E
SCHEMBL3272431 0.69 PSMD14 (0.61) ARACHEPARP1PSMD14COPS5
SCHEMBL19189304 0.68 KDM4E (0.62) ARPSMD14CYP1A2KDM4ETDP1
SCHEMBL7452926 0.67 CCR1 (0.67) PSMD14COPS5ALDH1A1CCR1CCR8
SCHEMBL18553852 0.66 KDM4E (0.42) ARPARP1PDE4APDE4BPDE4C
SCHEMBL16132489 0.64 CCR1 (0.61) ARACHEPARP1CYP1A2CYP2A6
SCHEMBL22126086 0.63 PARP1 (0.42) ARACHEPARP1PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5378711-A α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds BASF AKTIENGESELLSCHAFT (DE) 1995-01-03 US claimed
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
US-6200997-B1 CYCLIZATION TO GIVE OXAZOLIDINEDIONES AND TRIAZOLIDINEDIONES BASF AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
CN-1187814-A (hetero) aryloxy-, -thio-and-aminocrotonates, preparation and use thereof BASF AG (DE) 1998-07-15 CN disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed
US-5554578-A Oxime ether derivatives, their preparation and fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 1996-09-10 US disclosed
US-5468717-A Oxime ether derivatives, their preparation and fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 1995-11-21 US disclosed
US-5334577-A 2-(substituted pyridy-oxymethyl)-phenylglyoxylate alkyloxime BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US disclosed