SCHEMBL7954070

SCHEMBL7954070

COc1cccc2c(C)c[c]nc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 0.42
MAPT P10636 2/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
G6PD P11413 1/20 0.42
PKM P14618 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA1D P25100 1/20 0.40
ADRA1A P35348 1/20 0.40
ADRA1B P35368 1/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
ATP4A P20648 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3861841 0.80 CYP2A6 (0.42) MAPTKDM4EALDH1A1HTR1AADRA1D
SCHEMBL7954562 0.75 NR4A2 (0.41) LMNAKDM4EALDH1A1SMN1; SMN2
SCHEMBL5953588 0.72 ELANE (0.35) MAPTLMNAKDM4EALDH1A1HPGD
SCHEMBL1337689 0.71 HTR1A (0.61) NQO2MAPTNPC1LMNAPOLB
SCHEMBL18535287 0.70 KDM4E (0.59) NQO2MAPTNPC1LMNAPOLB
SCHEMBL5440649 0.69 LMNA (0.59) NQO2MAPTNPC1LMNAPOLB
SCHEMBL11195641 0.69 NQO2 (0.50) NQO2MAPTNPC1LMNAPOLB
SCHEMBL4467203 0.68 MCHR1 (0.51) NQO2MAPTNPC1LMNAPOLB
SCHEMBL9479911 0.68 NQO2 (0.50) NQO2MAPTNPC1LMNAPOLB
SCHEMBL16132474 0.67 CCR1 (0.57) HTR1AADRA1DADRA1AADRA1BATP4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
US-6200997-B1 CYCLIZATION TO GIVE OXAZOLIDINEDIONES AND TRIAZOLIDINEDIONES BASF AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed
US-5554578-A Oxime ether derivatives, their preparation and fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 1996-09-10 US disclosed
US-5468717-A Oxime ether derivatives, their preparation and fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 1995-11-21 US disclosed
US-5334577-A 2-(substituted pyridy-oxymethyl)-phenylglyoxylate alkyloxime BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US disclosed