Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954562 | 0.82 | NR4A2 (0.41) | CYP2A6CYP1A2PARP1KDM4EALDH1A1 | |
| SCHEMBL7952608 | 0.82 | AR (0.36) | CYP2A6CYP1A2PARP1KDM4EGAA | |
| SCHEMBL5953588 | 0.80 | ELANE (0.35) | CYP2A6CYP1A2ELANEKDM4EALDH1A1 | |
| SCHEMBL7954070 | 0.80 | NQO2 (0.42) | KDM4EHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7452926 | 0.71 | CCR1 (0.67) | L3MBTL1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL2300051 | 0.70 | OPRK1 (0.39) | CYP1A2ALDH1A1PSMD14COPS5KMT2A | |
| SCHEMBL2304470 | 0.67 | METAP2 (0.38) | CYP2A6ELANEPARP1GAAALDH1A1 | |
| SCHEMBL2301300 | 0.65 | MAPT (0.33) | CYP2A6CYP1A2ELANEPARP1KDM4E | |
| SCHEMBL2607397 | 0.65 | PSMD14 (0.68) | CYP2A6CYP1A2PARP1L3MBTL1HTR1A | |
| SCHEMBL8966258 | 0.64 | KDM4E (0.69) | CYP1A2ELANEPARP1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193168-B2 | Use of a TRPM5 inhibitor to regulate insulin and GLP-1 release | REDPOINT BIO CORPORATION (US) | 2012-06-05 | — | — | US | disclosed |
| EP-2107908-A2 | USE OF A TRPM5 INHIBITOR TO REGULATE INSULIN AND GLP-1 RELEASE | Redpoint Bio Corporation (US) | 2009-10-14 | — | — | EP | disclosed |
| US-20080306030-A1 | Use of a TRPM5 Inhibitor to Regulate Insulin and GLP-1 Release | REDPOINT BIO CORPORATION (US) | 2008-12-11 | — | — | US | disclosed |
| WO-2008097504-A2 | USE OF A TRPM5 INHIBITOR TO REGULATE INSULIN AND GLP-1 RELEASE | REDPOINT BIO CORPORATION (US) | 2008-08-14 | — | — | WO | disclosed |
| US-5677347-A | FUNGICIDES, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0669315-B1 | Ortho substituted phenylacetic acid amides | BASF AG (DE) | 1997-08-06 | — | — | EP | disclosed |
| US-5554578-A | Oxime ether derivatives, their preparation and fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| US-5523454-A | FUNGICIDES, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-04 | — | — | US | disclosed |
| US-5516804-A | FUNGICIDES FOR PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |
| EP-0477631-B1 | Ortho substituted phenylacetic acid amides | BASF AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| US-5468717-A | Oxime ether derivatives, their preparation and fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| EP-0669315-A1 | Ortho substituted phenylacetic acid amides | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-30 | — | — | EP | disclosed |
| US-5395854-A | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| US-5334577-A | 2-(substituted pyridy-oxymethyl)-phenylglyoxylate alkyloxime | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| EP-0477631-A1 | Ortho substituted phenylacetic acid amides | BASF Aktiengesellschaft (DE) | 1992-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306030-A1 | Use of a TRPM5 Inhibitor to Regulate Insulin and GLP-1 Release | GLP1R, GIPR, TRPM5 | CYP2A6 4275/4885CYP1A2 4676/4885ELANE 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.