Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676915 | 0.86 | EPHX2 (0.62) | EPHX2LIPEEPHX1HTR2AMEN1 | |
| SCHEMBL7953960 | 0.84 | HTR2A (0.47) | EPHX2LIPEEPHX1HTR2AMEN1 | |
| SCHEMBL7955680 | 0.81 | MEN1 (0.60) | EPHX2LIPEEPHX1MEN1KMT2A | |
| SCHEMBL7882037 | 0.76 | CA12 (0.40) | EPHX2LIPEEPHX1KMT2AMMP2 | |
| SCHEMBL8232185 | 0.76 | EPHX2 (0.84) | EPHX2EPHX1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7895732 | 0.76 | EPHX2 (0.51) | EPHX2LIPEEPHX1L3MBTL1DPP4 | |
| SCHEMBL2171815 | 0.74 | EPHX2 (0.61) | EPHX2LIPEEPHX1HTR2AMEN1 | |
| SCHEMBL424511 | 0.73 | EPHX2 (0.60) | EPHX2LIPEEPHX1MEN1KMT2A | |
| SCHEMBL1244796 | 0.72 | FFAR4 (0.50) | LIPE | |
| SCHEMBL1723334 | 0.71 | DPP4 (0.56) | LIPEMMP2L3MBTL1DPP4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346820-B1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO (JP) | 2013-02-13 | — | — | EP | disclosed |
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |