Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | LIPE | Q05469 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676915 | 0.88 | EPHX2 (0.62) | EPHX2MEN1KMT2ALIPEEPHX1 | |
| SCHEMBL421636 | 0.86 | EPHX2 (0.57) | EPHX2MEN1KMT2ALIPEEPHX1 | |
| SCHEMBL1677120 | 0.86 | EPHX2 (0.57) | EPHX2MEN1KMT2ALIPEEPHX1 | |
| SCHEMBL424511 | 0.86 | EPHX2 (0.60) | EPHX2MEN1KMT2ALIPEEPHX1 | |
| SCHEMBL7949461 | 0.86 | HSD11B1 (0.60) | EPHX2MEN1KMT2ALIPEEPHX1 | |
| SCHEMBL29460579 | 0.86 | MEN1 (0.62) | EPHX2MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL20456429 | 0.84 | USP2 (0.65) | EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18177501 | 0.84 | ALDH1A1 (0.70) | EPHX2MEN1KMT2ALIPENPC1 | |
| SCHEMBL27848166 | 0.83 | MEN1 (0.55) | EPHX2MEN1KMT2ALIPEEPHX1 | |
| SCHEMBL7955680 | 0.83 | MEN1 (0.60) | EPHX2MEN1KMT2ALIPEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346820-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | Shionogi & Co., Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |