Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | LIPE | Q05469 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1676915 | 0.92 | EPHX2 (0.62) | MEN1KMT2AEPHX2DPP4LIPE | |
| SCHEMBL2171815 | 0.83 | EPHX2 (0.61) | MEN1KMT2AEPHX2DPP4LIPE | |
| SCHEMBL19215178 | 0.83 | MEN1 (0.62) | MEN1KMT2AEPHX2DPP4LIPE | |
| SCHEMBL6329625 | 0.82 | PKM (0.64) | GAA | |
| SCHEMBL8206337 | 0.82 | PKM (0.64) | GAA | |
| SCHEMBL1677164 | 0.82 | MEN1 (0.58) | MEN1KMT2AEPHX2DPP4LIPE | |
| SCHEMBL1677161 | 0.82 | MEN1 (0.58) | MEN1KMT2AEPHX2DPP4LIPE | |
| SCHEMBL424511 | 0.81 | EPHX2 (0.60) | MEN1KMT2AEPHX2DPP4LIPE | |
| SCHEMBL7952744 | 0.81 | EPHX2 (0.48) | MEN1KMT2AEPHX2DPP4LIPE | |
| SCHEMBL421636 | 0.78 | EPHX2 (0.57) | MEN1KMT2AEPHX2DPP4LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |