SCHEMBL7952837

SCHEMBL7952837

CCc1ccc(B(O)O)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.48
LIPG Q9Y5X9 2/20 0.48
TRPA1 O75762 1/20 0.43
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
TAAR1 Q96RJ0 1/20 0.35
LMNA P02545 2/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MAP2K2 P36507 1/20 0.34
MAP2K1 Q02750 1/20 0.34
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533781 0.85 LPL (0.47) LPLLIPGTRPA1TAAR1LMNA
SCHEMBL2483099 0.84 LPL (0.52) LPLLIPGCA1CA2
SCHEMBL29730087 0.83 ENPP2 (0.44) LPLLIPGALDH1A1
SCHEMBL2855228 0.83 LPL (0.48) LPLLIPGTRPA1CYP1A2CYP2A6
SCHEMBL2295096 0.83 ENPP2 (0.44) LPLLIPGALDH1A1
SCHEMBL12883234 0.82 LPL (0.33) LPLLIPGALDH1A1
SCHEMBL31005872 0.82 CYP1A2 (0.34) LPLLIPGTRPA1CYP1A2ALDH1A1
SCHEMBL2299860 0.82 CYP1A2 (0.34) LPLLIPGTRPA1CYP1A2ALDH1A1
SCHEMBL31005873 0.82 CYP1A2 (0.34) LPLLIPGTRPA1CYP1A2ALDH1A1
SCHEMBL6555943 0.80 LIPG (0.56) LPLLIPGLMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110950743-B Difluoroethyleneoxy biphenyl diluent for high-birefringence liquid crystal and synthetic method thereof 陕西师范大学 2022-10-21 CN disclosed
CN-114350379-A Novel liquid crystal compound and preparation method and application thereof 北京八亿时空液晶科技股份有限公司 2022-04-15 CN disclosed
CN-110950743-A Difluoroethyleneoxy biphenyl diluent for high-birefringence liquid crystal and synthetic method thereof 陕西师范大学 2020-04-03 CN disclosed
EP-2673281-B1 BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF REMPEX PHARMACEUTICALS INC (US) 2016-04-13 EP disclosed
WO-2009137462-A2 METHODS FOR TREATING COGNITIVE DISORDERS USING INHIBITORS OF HISTONE DEACETYLASE ENVIVO PHARMACEUTICALS, INC. (US) 2009-11-12 WO disclosed