SCHEMBL7952899

SCHEMBL7952899

COCCCCC(C)(C)C(=O)CP(=O)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
ACLY P53396 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11467753 0.87
SCHEMBL9632329 0.86 FDPS (0.39) TSHR
SCHEMBL10357106 0.85 GGPS1 (0.42) TSHR
SCHEMBL9633798 0.85 GGPS1 (0.42) TSHR
SCHEMBL961898 0.84 FDPS (0.36) CYP4F2CYP4A11TSHR
SCHEMBL7951236 0.84 ALDH1A1 (0.37) ALDH1A1ARG1ARG2CYP4F2CYP4A11
SCHEMBL10357811 0.80 FDPS (0.33)
SCHEMBL7695204 0.76 PPARA (0.57)
SCHEMBL8114663 0.76 ARG1 (0.33) ALDH1A1ARG1ARG2TSHR
SCHEMBL10357188 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265440-B1 STOMACH ULCERS R-TECH UENO, LTD. (JP) 2001-07-24 US disclosed
US-5534547-A Prostaglandins of the D series, and tranquilizers and soporifics containing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1996-07-09 US disclosed
US-5428062-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1995-06-27 US disclosed
US-5137915-A PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-08-11 US disclosed
EP-0281239-B1 PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-03-25 EP disclosed
US-5073569-A 13,14-dihydro-15-keto- K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1991-12-17 US disclosed
EP-0281239-A2 Prostaglandins of the D series, and tranquilizers and soporifics containing the same Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-09-07 EP disclosed