SCHEMBL7952902

SCHEMBL7952902

COC(C)(C)CCCC(C)(C)C(=O)CP(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.33
LMNA P02545 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
MEN1 O00255 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
BLM P54132 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7951236 0.81 ALDH1A1 (0.37) GRM4LMNATDP1MEN1HPGD
SCHEMBL3741739 0.78 FDPS (0.44)
SCHEMBL10682984 0.77 FDPS (0.47)
SCHEMBL8114666 0.76 MEN1 (0.30) LMNATDP1MEN1HPGDTSHR
SCHEMBL7951208 0.76 GRM4 (0.33) GRM4LMNATDP1MEN1HPGD
SCHEMBL10683628 0.75 GGPS1 (0.50)
SCHEMBL10682391 0.75 GGPS1 (0.50)
SCHEMBL963978 0.75 ACACB (0.34) GRM4LMNATDP1MEN1HPGD
SCHEMBL10683719 0.74 FDPS (0.41) GRM4LMNATDP1MEN1HPGD
SCHEMBL8989476 0.73 TSHR (0.33) GRM4LMNATDP1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265440-B1 STOMACH ULCERS R-TECH UENO, LTD. (JP) 2001-07-24 US disclosed
US-5534547-A Prostaglandins of the D series, and tranquilizers and soporifics containing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1996-07-09 US disclosed
US-5428062-A Side effect reduction K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1995-06-27 US disclosed
US-5137915-A PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1992-08-11 US disclosed
EP-0281239-B1 PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-03-25 EP disclosed
US-5073569-A 13,14-dihydro-15-keto- K.K. UENO SEIYAKU OYO KENKYUJO (JP) 1991-12-17 US disclosed
EP-0281239-A2 Prostaglandins of the D series, and tranquilizers and soporifics containing the same Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-09-07 EP disclosed