Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989476 | 0.87 | TSHR (0.33) | GRM4LMNATDP1MEN1HPGD | |
| SCHEMBL16669156 | 0.80 | — | — | |
| SCHEMBL29639025 | 0.78 | TDP1 (0.36) | LMNATDP1TSHRKMT2AALDH1A1 | |
| SCHEMBL8989565 | 0.78 | GRM4 (0.32) | GRM4 | |
| SCHEMBL7952902 | 0.76 | GRM4 (0.33) | GRM4LMNATDP1MEN1HPGD | |
| SCHEMBL11849529 | 0.74 | TSHR (0.54) | LMNAMEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL8325012 | 0.74 | ALDH1A1 (0.55) | LMNATDP1MEN1HPGDTSHR | |
| SCHEMBL10259363 | 0.74 | TDP1 (0.34) | LMNATDP1ALDH1A1CYP3A4 | |
| SCHEMBL157395 | 0.74 | ALDH1A1 (0.48) | LMNATDP1MEN1TSHRKMT2A | |
| SCHEMBL7947621 | 0.74 | ALDH1A1 (0.43) | LMNATDP1MEN1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265440-B1 | STOMACH ULCERS | R-TECH UENO, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-5886034-A | ANTIULCER AGENTS | KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5770759-A | 13,14-DIHYDRO-15-KETO-PGF'S; VASOPRESSORS | R-TECH UENO, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5591887-A | 13,14-DIHYDRO-15-KETO-PGFS | R-TECH UENO, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5534547-A | Prostaglandins of the D series, and tranquilizers and soporifics containing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1996-07-09 | — | — | US | disclosed |
| US-5428062-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5380709-A | Prostaglandins E and anti ulcers containing same | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5284858-A | Prostaglandins E and anti ulcers containing same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5225439-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5221763-A | 13,14-dihydro-15-keto-PGFs and salts | R-TECH UENO, LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5166174-A | For duodenal ulcers or gastric ulcers | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0284180-B1 | PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-5137915-A | PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5106869-A | Vasopressor activity without ephemeral vasorelaxation; no effect on trachea, intestine | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0281239-B1 | PROSTAGLANDINS OF THE D SERIES, AND TRANQUILIZERS AND SOPORIFICS CONTAINING THE SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0289349-B1 | PROSTAGLANDINS OF THE F SERIES | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5073569-A | 13,14-dihydro-15-keto- | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0284180-A1 | Prostaglandins E and anti ulcers containing same | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-09-28 | — | — | EP | disclosed |
| EP-0281239-A2 | Prostaglandins of the D series, and tranquilizers and soporifics containing the same | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-09-07 | — | — | EP | disclosed |