Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259629 | 0.84 | USP2 (0.35) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL15689286 | 0.84 | LMNA (0.33) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL3645294 | 0.81 | LMNA (0.40) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL16915296 | 0.81 | LMNA (0.40) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL19512303 | 0.81 | LMNA (0.40) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL10507472 | 0.78 | LMNA (0.37) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL5868336 | 0.77 | — | — | |
| SCHEMBL27870207 | 0.72 | LMNA (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL11858560 | 0.72 | LMNA (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL28257916 | 0.72 | LMNA (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001062088-A2 | SAFENING HIGH CONCENTRATIONS OF PHYTOCATALYSTS | THE DOW CHEMICAL COMPANY (US) | 2001-08-30 | — | — | WO | disclosed |